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How AI Is Making Depression Diagnoses More Reliable

plus: Elon Musk’s Grok AI in Healthcare: Innovation or Ethical Minefield?

Happy Friday! It’s November 22nd.

Fortune just unveiled its list of the top 50 AI innovators for 2024, and eight of them are transforming healthcare. From DeepMind’s protein-folding breakthroughs to Xaira’s therapeutic innovations, these companies are changing how we understand and treat disease.

Our picks for the week:

  • Featured Research: How AI Is Making Depression Diagnoses More Reliable

  • Perspectives: The Real Cost of Ignoring Cybersecurity in Healthcare

  • Product Pipeline: Ultromics’ AI Device Gains FDA Approval for Cardiac Amyloidosis Detection

  • Policy & Ethics: Elon Musk’s Grok AI in Healthcare: Innovation or Ethical Minefield?

FEATURED RESEARCH

How AI Is Making Depression Diagnoses More Reliable

Illustration of a man who is depressed and sad, sitting on the floor in front of his couch.

Depression affects 280 million people globally, yet diagnosis often relies on subjective methods.

Researchers at Kaunas University of Technology (KTU) have developed an AI model that uses brain activity and speech patterns to identify depression with 97.53% accuracy.

This multimodal approach offers deeper, more objective insights into emotional states.

Fusing brain and voice data: The model combines EEG, which records brain activity, with speech analysis. EEG highlights neural patterns linked to mood, while speech reveals emotional cues like tone, pace, and energy.

Together, these data sources paint a clearer picture of depression than single methods can achieve.

Results that stand out: Tested on 52 participants, the AI achieved exceptional accuracy, precision, and recall, outperforming traditional methods.

Speech data provided unique insights that EEG alone couldn’t, offering a non-invasive, privacy-conscious alternative to facial recognition tools.

Looking ahead: This technology could make depression diagnosis faster and more accessible, particularly in underserved areas.

Challenges remain, including a need for explainable AI to ensure clinicians can trust and understand its results.

With refinement, this tool has the potential to complement clinical expertise and improve mental health care outcomes.

For more details: Full Article

Brain Booster

Humpback whales are famous for their haunting songs. Using AI, researchers recently uncovered surprising insights into these melodies. Which of the following was discovered?

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Select the right answer! (See explanation below)

Opinion and Perspectives

CYBERSECURITY

The Real Cost of Ignoring Cybersecurity in Healthcare

The healthcare industry faces mounting challenges as it grapples with surging cyberattacks, AI integration, and tightening regulations.

In just the first half of 2024, over 31 million Americans were impacted by health data breaches, including the record-setting Change Healthcare ransomware attack, which affected 100 million individuals.

These incidents highlight vulnerabilities in digital infrastructure, leaving many organizations struggling to safeguard patient data and maintain compliance.

Key challenges: A recent report surveying 120 healthcare leaders highlights critical issues:

  • Resource constraints: Over half of respondents cited limited budgets, staff, and technology as major barriers to compliance.

  • AI integration: While 75% of organizations are adopting or exploring AI for compliance tasks, only 42% report having governance frameworks to manage ethical and regulatory risks.

  • Cybersecurity threats: Ransomware and HIPAA violations dominate concerns, yet fewer than 50% of organizations conduct proactive audits.

What’s at stake: John E. Kelly, a healthcare compliance expert, emphasized that resource constraints, coupled with increasing risks, create a "challenging situation" for compliance effectiveness.

AI tools and proactive risk management offer potential solutions but demand investments many organizations lack.

Looking ahead: To adapt, healthcare providers are urged to adopt advanced threat-detection tools, strengthen AI governance, and collaborate with industry experts.

With compliance gaps widening, only forward-thinking strategies will meet the demands of an increasingly digital and regulated healthcare landscape.

For more details: Full Article

Top Funded Startups

Scroll down for the complete list.

Product Pipeline

HEART FAILURE DIAGNOSIS

Ultromics’ AI Device Gains FDA Approval for Cardiac Amyloidosis Detection

Ultromics has secured FDA clearance for EchoGo® Amyloidosis, an AI-powered echocardiography tool for early detection of Cardiac Amyloidosis, a frequently missed cause of heart failure. As the first device in the FDA's Total Product Lifecycle Advisory Program (TAP) to gain marketing authorization, it marks a milestone in diagnostic AI.

By analyzing a single routine echocardiographic clip, the device enhances diagnostic accuracy and reduces delays, particularly in resource-limited settings. Developed with Janssen Biotech and Pfizer, it delivers 84.5% sensitivity and 89.7% specificity in patients over 65 with heart failure, enabling earlier treatment and better outcomes in a condition where late diagnosis significantly limits therapeutic options.

For more details: Full Article

Policy and Ethics

MEDICAL ETHICS

Elon Musk’s Grok AI in Healthcare: Innovation or Ethical Minefield?

Elon Musk’s chatbot Grok has sparked debate over AI in healthcare. By analyzing user-submitted medical images, it aims to accelerate diagnostics. However, mixed results, such as misidentifying fractures, highlight its unreliability in clinical use.

Ethically, Grok’s data handling is troubling. X (formerly Twitter) is not bound by HIPAA, risking misuse of sensitive health data for marketing or discrimination. Experts warn against sharing medical data on non-regulated platforms.

To succeed in healthcare, AI tools like Grok require strict validation, privacy safeguards, and transparency. Without these, they risk harming patient trust and care quality, despite their potential benefits.

For more details: Full Article

Byte-Sized Break

📢 Three Things AI Did This Week

  • Google's Gemini AI chatbot allegedly told a user to "please die" during a discussion on aging, sparking outrage and forcing Google to address the alarming breach in its safety protocols. [Link]

  • Nvidia's quarterly earnings soared by 109%, driven by strong AI chip demand, but shares dipped 2.3% as investors questioned the sustainability of its growth. [Link]

  • The U.S. remains the global leader in AI innovation, with $67.2 billion in private investment last year, far surpassing China’s $7.8 billion. [Link]

Have a Great Weekend!

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💬 We read all of your replies, comments, and questions.

👉 See you all next week! - Bauris

Trivia Answer: A) The songs feature patterns resembling a form of grammar, much like human language.

Turns out, whales might be the poets of the ocean! Using AI, scientists found that humpback whale songs aren’t just random noise, they follow patterns resembling grammar, like verses in a song or lines in a play. Basically, whales could be out there composing underwater symphonies while we struggle with texting in full sentences.

How did we do this week?

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ICYMI - Snapshot

💰 Funded Startups Full List

  1. Enveda raised $130M in a Series C led by Kinnevik and FPV to advance its AI-driven, nature-based drug discovery pipeline, including 10 candidates and lead drug ENV-294, into clinical trials by 2025-2026. [Link]

  2. Jimini Health launched with $8M in pre-seed funding, led by Zetta Venture Partners and others, to revolutionize mental health care through a clinician-led therapy model supported by its supervised AI assistant, Sage. [Link]

  3. Citizen Health secured $14.5M in seed funding, led by Transformation Capital, and partnered with the Chan Zuckerberg Initiative's Rare As One Project to leverage AI in empowering patients and accelerating rare disease drug development. [Link]

  4. Homethrive raised $20M, led by Telus Global Ventures and 7wire Ventures, to expand its AI-enabled caregiver support platform and strengthen partnerships with payor organizations. [Link]

  5. DANNCE.AI raised $2.6M, led by LDV Capital, to commercialize its AI-driven motion analysis platform for neurological diagnostics and drug development, transforming clinical assessments with objective, 3D movement quantification. [Link]

  6. Synapticure raised $25M in Series A funding, led by B Capital and others, to expand its virtual care platform for neurodegenerative diseases, enhancing access to specialized care, AI-driven tools, and clinical trials across all 50 states. [Link]

  7. Cortechs.ai closed a Series C funding round, led by VILAS Ventures, to expand its AI-powered neuroimaging and prostate imaging solutions, enhance R&D, and broaden its commercial reach. [Link]

  8. Revisto secured $4M in seed funding, led by LiveOak Ventures and others, to enhance its AI-driven platform that streamlines pharmaceutical MLR reviews, reducing costs and accelerating marketing compliance. [Link]

  9. Mithrl raised $4M, led by Bonfire Ventures, to expand its AI-powered platform that accelerates scientific research by reducing data analysis time from months to minutes, enabling faster breakthroughs in drug discovery. [Link]

  10. Augere Medical raised NOK 23M ($2.1M) to enhance sales, marketing, and AI development for its PolypAID™ system, an AI-driven colorectal cancer screening tool recently CE-marked for the European market. [Link]

  11. Converge Bio raised $5.5M in seed funding led by TLV Partners to advance its generative AI platform, which uses biological language models to accelerate drug discovery and development for biotech and pharmaceutical companies. [Link]

  12. OneCell Diagnostics raised $16M in Series A funding led by Celesta Capital to expand its AI-driven blood biopsy technology for detecting cancer recurrence, focusing on scaling operations in the U.S. and India. [Link]

  13. Zarminali Health raised $40M led by General Catalyst to transform pediatric care with tech-enabled, coordinated primary and specialty services nationwide. [Link]

  14. New Lantern raised $19M in Series A funding led by Benchmark to launch its AI radiology suite, automating workflows to double radiologist efficiency and streamline patient care. [Link]

  15. FertilAI raised $4.5M led by Longevity Venture Partners and Redseed to expand its AI-driven fertility platform, enhancing clinical decision-making and improving patient outcomes. [Link]

Major Milestones - Partnerships, Products, and Approvals.

  1. Willow introduced Ema, an AI-powered support tool integrated into its app to provide personalized, expert-backed guidance and empathetic interaction for postpartum mothers, enhancing maternal health through technology. [Link]

  2. Lunit partnered with AstraZeneca to develop AI tools like SCOPE Genotype Predictor, speeding up NSCLC mutation detection and personalizing treatments. [Link]

  3. SpaceGut launched Malaysia's first AI-powered at-home gut health test, analyzing microbiome samples against 50,000 profiles to offer personalized insights and tackle rising gut health issues like metabolic syndrome. [Link]

  4. Cofactor Genomics launched OncoPrism-NSCLC, an AI-enabled RNA diagnostic validated to predict immunotherapy response in lung cancer patients, expanding its precision medicine offerings alongside Medicare-approved OncoPrism-HNSCC. [Link]

  5. Epigenic Therapeutics received approval to begin clinical trials for EPI-003, the first liver-targeted epigenetic therapy for chronic hepatitis B, leveraging its AI-powered EPIREG® platform to target HBV cccDNA and potentially offer a functional cure. [Link]

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